Ralph is executive chairman of Seminal HealthCare (Philadelphia), national advisor to Manatt, and senior fellow at LDI of Penn Medicine and Wharton (University of Pennsylvania). He is the retired chief executive officer, University of Pennsylvania Health System, where he served from 2003 - 2019. He was, from 1985 to 2001, the President of the University of Chicago Hospitals. Ralph is a Director of the National Committee for Quality Assurance (NCQA), NORC at the University of Chicago (NORC), and ECRI. He was a past Commissioner of the Joint Commission (TJC) and the Medicare Payment Advisory Commission (MedPAC), and served as Chairman of the Association of American Medical Colleges (AAMC), Chairman of the Council of Teaching Hospitals and Health Systems (COTH), Chairman of the University Healthsystem Consortium (UHC) and Chairman of NORC. He is a member of the National Academy of Medicine (NAM) and a Fellow of the American Association for the Advancement of Science (AAAS), and he is Chairman of the Philadelphia Orchestra and a Trustee of WHYY (Philadelphia NPR).